pentobarbital will lessen the level or result of mestranol by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
pentobarbital will decrease the level or outcome of aprepitant by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
pentobarbital will lessen the level or effect of guanfacine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Check Closely. Robust or reasonable CYP3A4 inducers considerably lessen guanfacine plasma concentrations and elimination 50 percent-existence.
pentobarbital will reduce the level or influence of pimavanserin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on. Avoid coadministration if possible. Keep an eye on for lessened pimavanserin efficacy. An increase in pimavanserin dosage might be essential.
Warning with use for the duration of surgeries or processes in youngsters more youthful than three yr or in pregnant Girls through their third trimester
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pentobarbital will reduce the extent or outcome of fostemsavir by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
pentobarbital will reduce the extent or impact of lumacaftor/ivacaftor by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
pentobarbital will lower the level or outcome of levonorgestrel oral/ethinylestradiol/ferrous bisglycinate by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep track of Intently. The efficacy of hormonal contraceptives could possibly be decreased.
pentobarbital will lessen the extent or influence of estrogens conjugated artificial by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track website of.
pentobarbital will lessen the extent or result of elagolix by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
pentobarbital will lessen the extent or outcome of larotrectinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will decrease the level or outcome of buprenorphine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
CYP3A4 inducers may enhance the development in the neurotoxic/nephrotoxic ifosfamide metabolite, chloroacetaldehyde. Closely observe sufferers using ifosfamide with CYP3A4 inducers for toxicities and consider dose adjustment.